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Test Code: BHC032
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Test Code: BHP025
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Test Code: BHU011
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Test Code: BHC069
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Test Code: BHC115
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Overview
Chronic Kidney Disease (CKD) also known as Chronic Renal Failure(CRF) encompasses all degrees of gradual loss of kidney function, from damaged–at risk through mild, moderate, and severe chronic kidney failure.
CKD is caused due to large number of systemic diseases (other organs of the body) that damage the kidney or from disorders that are intrinsic to the kidney itself
Scientifically speaking, a clinically significant CKD is defined as glomerular filtration rate (GFR) persistently below 60 mL/minute/1.73 m2
Glomerulus is the basic filtration unit of kidney and enables kidney to filter out wastes and excess fluids from blood, which are then excreted through urine; and in CKD dangerous levels of fluid, electrolytes and wastes build up in the body
Different stages of CKD are classified as:
Stage 1: Kidney damage with normal or increased GFR (>90 mL/min/1.73 m 2)
Stage 2: Mild reduction in GFR (60-89 mL/min/1.73 m 2)
Stage 3a: Moderate reduction in GFR (45-59 mL/min/1.73 m 2)
Stage 3b: Moderate reduction in GFR (30-44 mL/min/1.73 m 2)
Stage 4: Severe reduction in GFR (15-29 mL/min/1.73 m 2)
Stage 5: Kidney failure (GFR)
CKD is more prevalent in the elderly population; however, younger patients with CKD typically experience progressive loss of kidney function
Chronic kidney disease occurs when a disease or condition impairs kidney function, causing kidney damage to worsen over several months or years
Signs and symptoms of chronic kidney disease develop over time as and when the kidney damage progresses slowly:
Factors that increases risk of chronic kidney disease includes:
Chronic kidney disease can affect almost every part of your body. Potential complications may include:
To reduce risk of developing kidney disease:
Factors that increases risk of chronic kidney disease includes: